Planned Sessions

  • Deregulated glycolysis in cancer
  • PI3K/Akt/mTOR-, LKB1/AMPK- and deregulated FoxO signalling cascades
  • Autophagy, Apoptosis, Senescence and metabolic dysregulation
  • Hypoxia, p53 function and aberrant growth
  • Calorie restriction and differential stress response/chemosensitivity
  • Targeting cancer metabolism

Confirmed speakers

Name Institute/Country Field of research / Title of talk
Dario R. Alessi University of Dundee (UK) The structure and function of LKB1
Thorsten Cramer Charité, Berlin (D) Targeting metabolism and HIF-1 for cancer therapy
Benjamin F. Cravatt The Scripps Research Institute, La Jolla (USA) Mapping Dysregulated Metabolic Pathways in Cancer by Activity-Based Proteomics
Chi V. Dang Johns Hopkins University, Baltimore (USA) Myc, HIF1α and metabolism; lymphoma
Amato J. Giaccia Stanford University (USA) Targeting glucose transport as a targeted approach to treat renal cell cancer
Guido Kroemer INSERM Villejuif (F) Autophagy in stress adaptation, avoidance of cell death and longevity
Valter Longo University of Southern California (USA) Differential Cellular Protection and Sensitization in Cancer Treatment
Sybille Mazurek University of Giessen and ScheBo Biotech AG, Giessen (D) Bi-functional role of pyruvate kinase M2 within the tumor metabolome: Applications in diagnosis and potential for therapy
Wolfgang Mueller-Klieser Universität Mainz (D) Therapeutic aspects of tumor glycolysis
Masashi Narita Cancer Research UK Cambridge Research Institute (UK) Autophagy in cellular senescence
Markus Ralser Max-Planck-Institut für Genetik, Berlin (D) Regulatory adaptation to oxidative stress through a glycolysis/pentose phosphate pathway transition
Kevin Ryan Beatson Institute for Cancer Research, Glasgow (UK) Autophagy in the control of tumor cell death
David M. Sabatini MIT, Cambridge (USA) Akt, mTOR; multiple myeloma
Paolo Sassone-Corsi University of California, Irvine (USA) Circadian clock, signal transduction, metabolism, oncogenesis
Clemens A. Schmitt Charité, Berlin (D) Glucose metabolism, autophagy and senescence; lymphoma
Reuben J. Shaw The Salk Institute, La Jolla (USA) The LKB1/AMPK tumor suppressor pathway coordinates cell growth and metabolism
Matthew G. Vander Heiden Koch Institute at MIT, Cambridge, MA, USA Evidence for an alternate glycolytic pathway in cancer
Jean Zhao Harvard Medical School, Boston (USA) PI3K in cancer and metabolism