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Das Bild zeigt rechts ein Trichterglas mit blauer Flüssigkeit und Glasstab zum Umrühren. Daneben steht ein Reagenzglasständer mit Reagenzgläsern, die ebenfalls blaue Flüssigkeit enthalten. Im Hintergrund ist ein Forscher zu sehen, der in der rechten Hand eine Pipette hält.


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"Learning from the Yins and Yangs in Cancer"

24.+25. Mai 2019

Amano Rooftop Conference



Freitag, 24. Mai 2019


Sitzung I: DNA damage: tumor-protective or -promoting signal

09.30 – 10.00 Uhr         Willkommen / Einführung (Clemens A. Schmitt/Soyoung Lee)

10.00 – 10.30 Uhr         Björn Schumacher: Genome stability in aging and cancer 

10.30 – 11.00 Uhr         Christian Reinhardt: Targeting defects in the DNA damage Response for cancer therapy


11.00 – 11.15 Uhr         Kaffeepause


Sitzung II: Metabolic action - metabolic reaction

11.15 – 11.45 Uhr          Almut Schulze: Mevalonate pathway supports survival of p53-deficient cancer cells in metabolically restricted environments 

11.45 – 12.15 Uhr          Thomer Shlomi: Cancer cellular metabolism at a spatial-temporal resolution

12.15 – 12.45 Uhr          Inbal Mor: Metabolic adaption to prolonged resource exhaustion


12.45 – 14.15 Uhr          Mittag / Poster


Sitzung III: Resting cells - Re-initiating cells I

14.30 – 15.00 Uhr         Peter de Keizer: Targeting senescence against cancer and aging

15.00 – 15.30 Uhr         Raffaella di Micco: Dissecting the impact of cell senescence in the hematopoietic compartment

15.30 – 15.45 Uhr         Ismail Amr El-Shimy: Dissecting the effect of EGF starvation on EGFR signaling in the mouse small intestine using 3D organoid culture systems (Abstract talk)

15.45 – 16.00 Uhr         Cansu Yerinde: HDAC7 controls CD8+ T cell dependent anti-viral and anti-tumor immunity (Abstract talk)


16.00 – 16.30 Uhr          Kaffeepause


Sitzung IV: Resting cells - Re-initiating cells II


16.30 – 17.00 Uhr         Clemens A. Schmitt: Awakening dormancy - the evil side of senescence

17.00 – 17.30 Uhr         Ulrike Stein: Cancer metastasis, linking senescence and stemness

17.30 – 17.45 Uhr         Özcan Cinar: Development of MyD88 L256P mutation-specific TCR gene therapy for treatment of B-cell lymphoma and leukemia (Abstract talk)

17.45 – 18.00 Uhr         Maria Fernanda Lammoglia Cobo: Single cell identification of EBV epitope-specific T cell receptors for adoptive transfer against EBV infection and associated malignancies (Abstract talk)


19.30 Uhr                     Abendessen (Speakers' Dinner)


Samstag, 25. Mai 2019


Sitzung V: Tipping the homeostatic balance

09.00 – 09.30 Uhr         Gaetano Gargiulo: On Yins, Yangs, and Neoadjuvant targeted treatment in cancer

09.30 – 10.00 Uhr         Dorothy Sipkins:The yin and yang of leukemia cell metastases to the bone marrow: What goes in sometimes comes out 

10.00 – 10.30 Uhr         Melanie Werner-Klein: Dissemination of genetically immature cancer cells: and then?


10.30 – 10.45h             Kaffeepause


Sitzung VI: Tumor-promoting vs. tumor-suppressive inflammatory signaling? 

10.45 – 11.15 Uhr         Andrea Ablasser: Targeting STING in senescence

11.15 – 11.45 Uhr         Jesus Gil: The senescence-associated secretory phenotype (SASP), linking senescence cancer and inflammation

11.45 – 12.15 Uhr         Round table discussion: tumor-suppressive or -promoting? Killing or arresting cancer cells? Aging or renewal? Preventing or overtreatment? Stemness or Differentiation?

                                    Debaters: selected speakers with vivid audience participation


12.15 – 13.00h              Mittag


Sitzung VII: Tracking and tackling state and fate

13.00 – 13.30 Uhr          Rosalie Sears: Dynamic mechanisms controlling cell lineage plasticity and therapeutic resistance in pancreatic ductal adenocarcinoma

13.30 – 14.00 Uhr          Rune Linding: Deep decoding of network attacking mutations rewiring cancer

14.00 – 14.30 Uhr          Zeyneb Altintas: NanoMIP applications in cancer diagnosis

14.30 – 14.45 Uhr          Abschluss


14.45 – 15:45 Uhr         Poster und Kaffee